阿西替尼
中文同義詞:N-甲基-2-((3-((1E)-2-(吡啶-2-基)乙烯)-1H-吲唑-6-基)硫)甲酰胺
英文名稱:Axitinib
英文同義詞:AXITINIB;Benzamide, N-methyl-2-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]thio]-;N-METHYL-2-{[3-((E)-2-PYRIDIN-2-YLVINYL)-1H-INDAZOL-6-YL]SULFANYL}BENZAMIDE;N-Methyl-2-((3-((1E)-2-(pyridin-2-yl)ethenyl)-1H-indazol-6-yl)sulfanyl)benzamide;AVERMECTINB;Axitinib for research;AG 013736;N-Methyl-2-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]thio]benzamide
CAS號(hào): 319460-85-0
分子式:C22H18N4OS
分子量:386.47
用途：阿西替尼可阻止對(duì)腫瘤生長(zhǎng)和轉(zhuǎn)移起作用的某些被稱為激酶的蛋白發(fā)揮作用。
阿西替尼是一種小分子酪氨酸激酶抑制劑，對(duì)多個(gè)靶點(diǎn)有效，包括VEGF受體1,2和3。 
包裝：按客戶需求
銷售價(jià)格：650/g

Product Name:     Axitinib    

Synonyms:     AXITINIB;Benzamide, N-methyl-2-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]thio]-;N-METHYL-2-{[3-((E)-2-PYRIDIN-2-YLVINYL)-1H-INDAZOL-6-YL]SULFANYL}BENZAMIDE;N-Methyl-2-((3-((1E)-2-(pyridin-2-yl)ethenyl)-1H-indazol-6-yl)sulfanyl)benzamide;AVERMECTINB;Axitinib for research;AG 013736;N-Methyl-2-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]thio]benzamide    

CAS:     319460-85-0    

MF:     C22H18N4OS    

MW:     386.47    

Product Categories:     All Inhibitors;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;Protein Kinase Inhibitors and Activators;Pfizer compounds

Chemical Properties     Off-White Solid    

Assay 99%

Usage     A tyrosine kinase inhibitor; used in cancer therapy.    Axitinib (AG-013736) is a multi-target inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFRβ and c-Kit with IC50 of 0.1 nM, 0.2 nM, 0.1-0.3 nM, 1.6 nM and 1.7 nM, respectively.    

Packing  1kg /foli bag